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Prophylaxis of chemically induced papillomas and carcinomas of mouse skin by vitamin A-Acid

✍ Scribed by W. Bollag

Book ID
112658071
Publisher
Springer
Year
1972
Tongue
English
Weight
243 KB
Volume
28
Category
Article
ISSN
1420-682X

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## Abstract The Tg.AC transgenic mouse carries a v‐Ha‐__ras__ transgene. Skin papillomas develop in Tg.AC mice upon repeated dermal application of tumor promoters and carcinogens. The transgene is inserted at a single site on chromosome 11 in a multiple‐copy array. Although most of the β‰₯ 40 copies