Polyglutamine-induced ion channels: a po
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Yutaka Hirakura; Rustam Azimov; Rushania Azimova; Bruce L. Kagan
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Article
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2000
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John Wiley and Sons
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English
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CAG repeats resulting in long polyglutamine tracts have been implicated in the pathogenesis of at least eight neurodegenerative diseases including Huntington. Expression of polyglutamine repeats is required for disease and increasing length of the repeats leads to earlier onset of illness (anticipat