Prophylactic trypsin inhibition during the isolation procedure guarantees reproducible, high porcine islet yields

Isolation of porcine pancreatic islets:

Isolation of porcine pancreatic islets: Low trypsin activity during the isolation procedure guarantees reproducible high islet yields

✍ Dr. Axel Heiser; Karin Ulrichs; Wolfgang Müller-Ruchholtz 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 417 KB

During the past few years, interest in xenotransplantation of porcine islets of Langerhans for the future therapy of type I diabetes has increased markedly. Therefore, we established a semiautomated digestion method for isolating islets from the porcine pancreas. However, although the isolation tech