Prophylactic endovascular radiotherapy to prevent intimal hyperplasia after stent implantation in femoropopliteal arteries

✍ Scribed by Dieter Liermann; Heinz D. Bottcher; Jürgen Kollath; Bernd Schopohl; Gerd Strassmann; Ernst-P. Strecker; Karl H. Breddin

• Book ID: 104659885
• Publisher: Springer
• Year: 1994
• Tongue: English
• Weight: 587 KB
• Volume: 17
• Category: Article
• ISSN: 1432-086X
• DOI: 10.1007/bf00197908

✦ Synopsis

Purpose: Recurrent stenosis or occlusion by intimal hyperplasia occurs in up to 40% of patients with tantalum stent implantations in femoropopliteal arteries and greatly restricts their usefulness. We evaluated the effect of prophylactic endovascular radiotherapy on stenosed/occluded stents. Methods: We investigated prophylactic endovascular radiotherapy with a surface dose of 12 Gy using an iridium 192 source as a means to reduce or eliminate recurrent stenosis in 4 patients with stenosed/occluded stents, 6-8 months after the original implantation. Confirmatory diagnostic atherectomy, PTA or laser recanalization and endovascular radiol:herapy were performed.

Results: None of the four has developed recurrent obstruction within 23 to 30 months after this treatment, which up to now shows no short-term or long-term complications.

Conclusion:

We conclude that this limited experience is promising enough to warrant further study.