Prophylactic and therapeutic vaccination with dendritic cells against hepatitis C virus infection
β Scribed by J. Encke; J. Findeklee; J. Geib; E. Pfaff; W. Stremmel
- Book ID
- 108699226
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 270 KB
- Volume
- 142
- Category
- Article
- ISSN
- 0009-9104
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Chronic evolution of acute hepatitis C (aHC) occurs in more than 80% of patients but can frequently be prevented by early treatment with interferon (IFN)-alpha. Plasmacytoid dendritic cells (pDCs) are the major endogenous IFN-alpha producers, but their role in aHC is unknown. In this study, frequenc
A high incidence of community-acquired hepatitis C virus infection that can lead to the progressive development of chronic active hepatitis, liver cirrhosis, and primary hepatocellular carcinoma occurs throughout the world. A vaccine to control the spread of this agent that represents a major cause