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Prophenin-1, an exceptionally proline-rich antimicrobial peptide from porcine leukocytes

✍ Scribed by Sylvia S.L Harwig; Vladimir N Kokryakov; Kristine M Swiderek; Galina M Aleshina; Chengquan Zhao; Robert I Lehrer


Book ID
115930603
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
508 KB
Volume
362
Category
Article
ISSN
0014-5793

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We determined the cysteine connectivity of protegrin PG-2, a leukocyte-derived antimicrobial peptide, by performing sequential enzyme digestions with chymotrypsin and thermolysin, and monitoring each digest by direct liquid chromatography-electrospray mass spectrometric analysis. This approach resol