Synthesis, biological and biochemical pr
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A. Bargiotti; A. M. Casazza; G. Cassinelli; A. Marco; S. Penco; G. Pratesi; R. S
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Article
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1983
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Springer
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English
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New 4'-C-methyl analogues of daunorubicin, synthesized by the coupling reaction of daunomycinone with 1-chloroderivatives of protected 4-C-methyldaunosamine analogues, were chemically transformed to the corresponding doxorubicin analogues. Their cytotoxic effect against HeLa cells, ability to bind t