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Properties of the microsomal and cytosolic glutathione transferases involved in hexachloro-1:3-butadiene conjugation

✍ Scribed by Franz Oesch; C.Roland Wolf


Book ID
115780797
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
731 KB
Volume
38
Category
Article
ISSN
0006-2952

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## ABSTRACT Hexachloro‐1:3‐butadiene (HCBD) causes kidney injury specific to the __pars recta__ of the proximal tubule. In the present studies, injury to the nephron was characterized at 24 h following a single dose of HCBD, using a range of quantitative urinary measurements, renal histopathology a