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Properties of the Dark and Signaling States of Photoactive Yellow Protein Probed by Solution Phase Hydrogen/Deuterium Exchange and Mass Spectrometry †

✍ Scribed by Cheng, Guilong; Cusanovich, Michael A.; Wysocki, Vicki H.

Book ID
127255212
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
296 KB
Volume
45
Category
Article
ISSN
0006-2960

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The rates at which hydrogens located at peptide amide linkages in proteins undergo isotopic exchange when a protein is exposed to depend on whether these amide hydrogens are hydrogen bonded and whether they are D 2 O accessible to the aqueous solvent. Hence, amide hydrogen exchange rates are a sensi