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Properties of the chromatin repair activity against O6-ethylguanine lesions in DNA : Mechanism of the reaction

✍ Scribed by André RENARD; Walter G. VERLY; Jitendra R. MEHTA; David B. LUDLUM

Book ID
115122089
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
709 KB
Volume
136
Category
Article
ISSN
1432-1327

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## Abstract Bulky DNA damage is corrected by the nucleotide excision repair (NER) pathway. Although the core biochemical mechanism of NER is understood, details including lesion recognition and repair in the context of chromatin remain to be elucidated. As more data become available, the complexity