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Properties of end-stage human T cells defined by CD45RA re-expression

✍ Scribed by Sian M Henson; Natalie E Riddell; Arne N Akbar


Book ID
119219703
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
464 KB
Volume
24
Category
Article
ISSN
0952-7915

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## Abstract T cell activation requires costimulation of TCR/CD3 plus accessory receptors (__e.g.__ CD28). A hallmark of costimulation is the dynamic reorganization of the actin cytoskeleton, important for receptor polarization in the immunological synapse. The classical model of T cell costimulatio