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Properties of a Soluble DNA Polymerase Isolated from Rous Sarcoma Virus

โœ Scribed by Peter Duesberg, Klaus V. D. Helm and Eli Canaani

Book ID
123650221
Publisher
National Academy of Sciences
Year
1971
Tongue
English
Weight
882 KB
Volume
68
Category
Article
ISSN
0027-8424

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T h e DNA polymerase ("reverse transcriptase") has been isolated from virions of two temperature-sensitive Rous sarcoma virus mutants (ts335 a n d ts337). These mutants are defective a t a n early stage of both growth a n d transformation. The purified polymerase is three-fold more rapidly inactivat