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Properties of a hybrid between lines sensitive and insensitive to contact inhibition of cell division

✍ Scribed by Mary C. Weiss; George J. Todaro; Howard Green

Publisher: John Wiley and Sons
Year: 1968
Tongue: English
Weight: 228 KB
Volume: 71
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040710112

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✦ Synopsis

Hybrid cell lines have been prepared between 3T3, a line highly sensitive to contact inhibition of division, and cl I-D, an L cell derivative which is not sensitive. A number of hybrid clones isolated were found to be quite sensitive, indicating that i n this respect the 3T3 behavior is the more fully expressed i n the hybrid. On serial subculture, the hybrid lines gave rise to variants less sensitive to contact inhibition,

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