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Proof of RNA Interference in Humans after Systemic Delivery of siRNAs

✍ Scribed by Jens Kurreck


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
216 KB
Volume
49
Category
Article
ISSN
0044-8249

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## Abstract C‐terminal Src kinase (Csk) controls the Src family kinase Lck, which is essential for T cell antigen receptor (TCR)‐mediated signaling. For the first time, we here report the effects of acuteelimination of Csk in Jurkat T cells and primary T cells using short interfering (si) RNA. In b