A number of different crosses between strains of Saccharomyces cerevisiae differing in mitochondrial genotype are analyzed with respect to the extent to which individual zygotes transmit mitochondrial genes from one parent or the other. Many crosses produce two or more distinct classes of zygotes in
โฆ LIBER โฆ
Promotion of uniparental inheritance of mitochondrial drug resistance by delayed division of yeast zygotes
โ Scribed by Wolf, K. ;Del Giudice, L. ;Kaudewitz, F.
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 180 KB
- Volume
- 176
- Category
- Article
- ISSN
- 0026-8925
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โฆ Synopsis
Uniparental inheritance of mitochondrial markers conferring resistance to 3 (3,4-dichlor-phenyl)-1,1-dimethylurea (diuron or DCMU) and antimycin in the fission yeast Schizosaccharomyces pombe is promoted by delaying first division of zygotes.
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Pairs of strains of opposite mating type were isolated from a strain of Saccharomyces cerevisiae. From these isogenic strains, mitochondrially inherited resistant mutants to antimycin A and erythromycin were isolated. By using the two resistance genes as mitochondrial markers, it was proposed that t