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Promotion of activation of bovine trypsinogen by specific modification of aspartyl residues

โœ Scribed by Radhakrishnan, T. M.; Walsh, Kenneth A.; Neurath, Hans


Book ID
127066109
Publisher
American Chemical Society
Year
1969
Tongue
English
Weight
879 KB
Volume
8
Category
Article
ISSN
0006-2960

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The preparation of /3-trypsin can be simply accomplished from the activation of bovine trypsinogen with partially purified enterokinase in the presence of STI-Sepharose. Enterokinase catalyzes the specific cleavage of lysine 6-isoleucine 7 and the presence of ST1 prevents autolysis of /3-trypsin by