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Promotion of acid-induced membrane fusion by basic peptides. Amino acid and phospholipid specificities

✍ Scribed by Jan Bondeson; Roger Sundler

Book ID
115729275
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
686 KB
Volume
1026
Category
Article
ISSN
0005-2736

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It was previously found that a cationic amphiphilic peptide, Ac-(Leu-Ala-Arg-Leu) 3 -NHCH 3 (4 3 ), caused the destabilization of a phospholipid membrane and showed strong antibacterial activity [Lee et al. Biochim. Biophys. Acta 1986; 862: 211 -219]. In order to investigate the effect of changing h