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Promotion by ascorbic acid, sodium erythorbate and ethoxyquin of neoplastic lesions in rats initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine

โœ Scribed by Fukushima, Shoji; Kurata, Yasushi; Shibata, Masa-Aki; Ikawa, Etsuo; Ito, Nobuyuki


Book ID
122339899
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
634 KB
Volume
23
Category
Article
ISSN
0304-3835

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Hepatocarcinogenic activity of N-butyl-N
โœ A. Hagiwara; T. Murai; H. Yoshino; H. Goshima; S. Mori; A. Takashima; T. Shirai; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 164 KB

Male F344 and Wistar Shionogi (WS) rats were treated with 0.05% N-butyl-N-(4hydroxybutyl)nitrosamine (BBN) for 20 weeks and then killed at week 36 (experiment 1). Although reduction of body weight increase was found, no effects on liver weights were noted. Formalin-fixed and paraffin-embedded liver