Tumor-infiltrating IL-17-producing γδ T
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Daiko Wakita; Kentaro Sumida; Yoichiro Iwakura; Hiroyoshi Nishikawa; Takayuki Oh
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Article
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2010
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John Wiley and Sons
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English
⚖ 528 KB
## Abstract Based on the evidence that IL‐17 is a key cytokine involved in various inflammatory diseases, we explored the critical role of IL‐17‐producing γδ T cells for tumor development in tumor‐bearing mouse model. IL‐17^−/−^ mice exhibited a significant reduction of tumor growth, concomitantly