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Promoter methylation study of theH37/RBM5tumor suppressor gene from the 3p21.3 human lung cancer tumor suppressor locus

✍ Scribed by Juliana J. Oh; Baher N. Boctor; Cynthia A. Jimenez; Roberto Lopez; Ashley K. Koegel; Eileen O. Taschereau; Diana T. Phan; Steven E. Jacobsen; Dennis J. Slamon

Book ID: 106134635
Publisher: Springer
Year: 2007
Tongue: English
Weight: 464 KB
Volume: 123
Category: Article
ISSN: 0340-6717
DOI: 10.1007/s00439-007-0449-5

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## Abstract ## BACKGROUND Imprinted tumor suppressor genes may be particularly important in the pathogenesis of ovarian cancer. Two imprinted genes, paternally expressed 3 (__PEG3__) and aplasia Ras homologue member I (__ARHI__), are the most frequently down‐regulated in ovarian cancers on gene ex