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Promoter hypomethylation upregulates Na+–K+–2Cl− cotransporter 1 in spontaneously hypertensive rats

✍ Scribed by Hae-Ahm Lee; Inji Baek; Young Mi Seok; Enyue Yang; Hyun-Min Cho; Dong-Youb Lee; Su Hyung Hong; In Kyeom Kim

Book ID
116300206
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
537 KB
Volume
396
Category
Article
ISSN
0006-291X

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## Abstract Disruption of periciliary fluid homeostasis is the main pathogenesis of otitis media with effusion (OME), one of the most common childhood diseases. Although the underlying molecular mechanisms are unclear, it has been suggested that the altered functions of ion channels and transporter