Promoter hypermethylation of CCNA1, RARRES1, and HRASLS3 in nasopharyngeal carcinoma
โ Scribed by Pattamawadee Yanatatsaneejit; Thep Chalermchai; Veerachai Kerekhanjanarong; Kanjana Shotelersuk; Pakpoom Supiyaphun; Apiwat Mutirangura; Virote Sriuranpong
- Book ID
- 113832904
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 556 KB
- Volume
- 44
- Category
- Article
- ISSN
- 1368-8375
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๐ SIMILAR VOLUMES
## Abstract To identify the epigenetic changes in nasopharyngeal carcinoma (NPC), we performed methylationโsensitive restriction fingerprinting (MSRF) analysis on NPC cell lines and xenografts. A 190 bp sequence methylated in NPC tumors was isolated and showed high homology to the 5โฒ CpG island of
## Abstract Tazaroteneโinduced gene 1 (__TIG1__) and Tazaroteneโinduced gene 3 (__TIG3__) are retinoid acid (RA) target genes as well as candidate tumor suppressor genes in human cancers. In our study, we have investigated the expression of __TIG1__ and __TIG3__ in nasopharyngeal carcinoma (NPC). L