𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines

✍ Scribed by Ku, Ja-Lok; Kang, Sung-Bum; Shin, Young-Kyoung; Kang, Hio Chung; Hong, Sung-Hye; Kim, Il-Jin; Shin, Joo-Ho; Han, Inn-Oc; Park, Jae-Gahb


Book ID
118676949
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
272 KB
Volume
23
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Promoter hypermethylation of the ADAM23
✍ Jin-Sung Choi; Kyung-Hee Kim; You-Kyung Jeon; Sung-Hee Kim; Sang-Geun Jang; Ja-L πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 477 KB πŸ‘ 2 views

## Abstract Promoter hypermethylation of the __ADAM23__ gene, which is normally involved in cell‐to‐cell and cell‐to matrix adhesion, has been reported in pancreatic, breast and brain cancer, and recently the role of this gene was examined in gastric cancer. In this study, we analyzed __ADAM23__ ex

Role of hMLH1 promoter hypermethylation
✍ Christian N. Arnold; Ajay Goel; C. Richard Boland πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 432 KB πŸ‘ 1 views

## Abstract Loss of DNA mismatch repair (MMR) occurs in 10–15% of sporadic colorectal cancer, is usually caused by hMLH1 hypermethylation, and has been shown to confer resistance to various chemotherapeutic reagents, including 5‐fluorouracil (5‐FU). We tested the hypothesis that demethylation of th