Promoter hypermethylation and expression profile of MGMT and CDH1 genes in oral cavity cancer
โ Scribed by Dor Mohammad Kordi-Tamandani; Abdul-Karim Moazeni-Roodi; Mohammad-Ayub Rigi-Ladiz; Mohammad Hashemi; Elnaz Birjandian; Adam Torkamanzehi
- Book ID
- 113466320
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 157 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0003-9969
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Aberrant promoter hypermethylation of tumorโassociated genes leading to their inactivation is a common event in many cancer types. Using a sensitive restrictionโmultiplex PCR method, we studied the promoter hypermethylation profile of the __p16, p15, hMLH1, MGMT__ and __Eโcad__ genes in
## Abstract Allelic losses on the chromosome arms 1p and 19q have been associated with favorable response to chemotherapy and good prognosis in anaplastic oligodendroglioma patients, but the molecular mechanisms responsible for this relationship are as yet unknown. The DNA repair enzyme O^6^โmethyl