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Promoter haplotype combinations for the human PDGFRA gene are associated with risk of neural tube defects

✍ Scribed by Huiping Zhu; Ned J Wicker; Kelly Volcik; Jing Zhang; Gary M Shaw; Edward J Lammer; Lucina Suarez; Mark Canfield; Richard H Finnell


Book ID
116987443
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
217 KB
Volume
81
Category
Article
ISSN
1096-7192

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## Communicated by Stephen Chanock Matrix metalloproteinases (MMPs) play important roles in cancer initiation and development. Several polymorphisms in the promoters of a number of MMP genes, which can affect the respective MMP production in an allele-specific manner, have been well characterized.