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Promoter CpG hypomethylation and transcription factor EGR1 hyperactivate heparanase expression in bladder cancer

โœ Scribed by Ogishima, Tatsuya; Shiina, Hiroaki; Breault, Julia E; Terashima, Masaharu; Honda, Satoshi; Enokida, Hideki; Urakami, Shinji; Tokizane, Takashi; Kawakami, Toshifumi; Ribeiro-Filho, Leopoldo A

Book ID
110069855
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
318 KB
Volume
24
Category
Article
ISSN
0950-9232

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## Abstract Hereditary nonpolyposis colorectal cancers (HNPCCs) are an important subgroup of colorectal carcinomas. Compared to sporadic variants, they present several particular features, the most important of which are less invasive and metastatic properties linked to a more favorable prognosis.