## Abstract Induction of T cell tolerance in the thymus (central tolerance) is essential for preventing organβspecific autoimmunity. This apparent paradox is in part explained by promiscuous expression of numerous tissueβrestricted selfβantigens (TRA) in medullary thymic epithelial cells (mTEC), wh
β¦ LIBER β¦
Promiscuous expression of tissue antigens in the thymus: a key to T-cell tolerance and autoimmunity?
β Scribed by Ludger Klein; Bruno Kyewski
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 187 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0946-2716
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