A case of prolymphocytic transformation of chronic lymphocytic leukemia (CLL) is presented in which complete peripheral morphometric remission and lengthy survival were observed after intensive chemotherapy. The case is discussed within the context of the reported therapeutic experience.
Prolonged survival in chronic lymphocytic leukemia: A case report
โ Scribed by Reynolds, Colonel Ralph D. ;Horne, Major McDonald K. ;Greenberg, Bernard R. ;Mackenzie, Malcolm R. ;Binder, Henry J. ;Chang, R. Shihman ;Lawrence, John H.
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 261 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0098-1532
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โฆ Synopsis
A patient with long-standing chronic lymphocytic leukemia with both humoral and cellular immunodeficiency had lymph node receptor evidence of a B lymphocyte disorder. He was also found to secrete the Epstein--Barr virus and, late in his illness, developed a markedly positive antinuclear antibody. Interrelationship of these findings may be important in the ultimate determination of the etiology and functional mechanisms in lymphocyte malignancies.
๐ SIMILAR VOLUMES
Four patients who demonstrated unusually prolonged survival with Philadelphia chromosome positive Ph' (+) chronic myeloid leukemia (CML) were analyzed for factors associated with survival. Survival duration from initial diagnosis ranged from 120 to 222 months, with a mean of 170 months. At diagnosis