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Prolonged seizure activity leads to increased Protein Kinase A activation in the rat pilocarpine model of status epilepticus

✍ Scribed by James M. Bracey; Jonathan E. Kurz; Brian Low; Severn B. Churn

Book ID
113504312
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
477 KB
Volume
1283
Category
Article
ISSN
0006-8993

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## Abstract The epileptic brain is characterized by increased susceptibility to neuronal hyperexcitability. The rat lithium‐pilocarpine model, which mimics many features of temporal lobe epilepsy, has been used to study processes leading to the development of recurrent seizures. After a prolonged s