Prolonged remissions in adults with acute leukemia following late intensification chemotherapy and immunotherapy
β Scribed by Gerald P. Bodey; Emil J. Freireich; Kenneth B. McCredie; Jordan U. Gutterman; Evan M. Hersh; Terry L. Smith; Edmund A. Gehan
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 816 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## BACKGROUND. Significant controversy surrounds the use of remission induction chemotherapy (IC) in older adults with acute myeloid leukemia (AML). Earlier clinical trials have yielded conflicting results and possibly a minor survival benefit, often offset by a longer hospitalization
To determine whether lithium can shorten chemotherapy-induced neutropenia, 35 adult patients with newly diagnosed acute myeloid leukemia undergoing initial chemotherapy were randomized either to receive oral lithium started at the time of biopsy-proven hypoplasia or to receive no lithium. This study
## Abstract The most important problem in the therapy of patients with acute myeloid leukemia (AML) is relapse after intensive therapy. We sought to determine if interleukinβ2 (lowβdose with intermittent boluses) administration could be feasibly administered after standard therapy to potentiate ant