Repression of mitogen-activated protein
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Kailesh Gopalbhai; Sylvain Meloche
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Article
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1998
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John Wiley and Sons
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English
⚖ 519 KB
The observation that mitogen-activated protein (MAP) kinases ERK1 and ERK2 are constitutively activated in a number of oncogene-transformed cell lines has led to the hypothesis that prolonged activation of these enzymes is required for the transformation process. To investigate this question, we hav