Proliferation inhibition of cisplatin and aquaporin 5 expression in human ovarian cancer cell CAOV3
✍ Scribed by Jianhua Yang; Chunxiao Yan; Wei Zheng; Xuejun Chen
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 489 KB
- Volume
- 285
- Category
- Article
- ISSN
- 0003-9128
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Resistance to cisplatin‐based chemotherapy is a major cause of treatment failure in human ovarian cancer. Wild‐type __TP53__ status is often, but not always, associated with cisplatin sensitivity, suggesting that additional factors may be involved. Overexpression/activation of the phosp
## Abstract Human ovarian carcinoma cells (2008 and its cisplatin‐resistant sub‐line 2008/C13\*) were sensitized to cisplatin by treatment with human recombinant gamma interferon (IFNγ). IFNγ produced no significant change in the uptake of CDDP. Exposure of 2008 and 2008/C13\* cells to IFNγ resulte
## Abstract Lipocalin‐type prostaglandin D synthase (LPGDS; PGH~2~D‐isomerase; EC 5.3.99.2) is a bifunctional protein first identified in the mammalian brain. It acts as a PGD~2~‐producing enzyme and a retinoid transporter. Recent studies have shown that LPGDS is anomalously expressed in ovarian tu
## Abstract ## BACKGROUND Endometrial cancer is a common gynecologic malignancy among women. The molecular mechanisms involved in the progression of endometrial cancer are unclear, which has hampered the development of an effective treatment. Survivin, a newly identified member of the inhibitor of