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Proliferation and differentiation in the human breast during pregnancy

✍ Scribed by Rami Suzuki; Amanda J. Atherton; Michael J. O'Hare; Catherine Clarke; Alan Entwistle; Sunil R. Lakhani

Book ID
114428680
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
320 KB
Volume
66
Category
Article
ISSN
0301-4681

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## Abstract Human mesenchymal stem cells (MSCs) reside under hypoxic conditions in vivo, between 4% and 7% oxygen. Differentiation of MSCs under hypoxic conditions results in inhibited osteogenesis, while chondrogenesis is unaffected. The reasons for these results may be associated with the inheren