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Prolactin-Dependent Up-Regulation ofBRCA1Expression in Human Breast Cancer Cell Lines

✍ Scribed by David A. Favy; Pascale Rio; Jean-Claude Maurizis; Candan Hizel; Yves-Jean Bignon; Dominique J. Bernard-Gallon

Book ID
115583709
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
133 KB
Volume
258
Category
Article
ISSN
0006-291X

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The EMS1 gene encodes an 80185 kDa C-src substrate and localises with the CCNDl gene to chromosome I lq13. This locus is amplified in approximately 13% of human breast cancers. E M S I gene amplification and expression were charactensed in a panel of human breast cancer cell lines to determine at wh