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Proinflammatory Cytokine Expression in Cyclooxygenase-2–deficient Primary Osteoblasts

✍ Scribed by Jianing He; Rosamond Tomlinson; David Coon; Ajay Gulati; Cameron Cowan

Book ID
116676989
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
312 KB
Volume
33
Category
Article
ISSN
0099-2399

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## Abstract ## Objective Bradykinin (BK) stimulates bone resorption in vitro and synergistically potentiates interleukin‐1 (IL‐1)–induced bone resorption and prostaglandin (PG) formation, suggesting that kinins are important in inflammation‐induced bone loss. The present study was undertaken to st