✦ LIBER ✦
Progressive supranuclear palsy-like phenotype associated with bilateral hypoxic–ischemic striopallidal lesions
✍ Scribed by Hee Tae Kim; Simon Shields; Kailash P. Bhatia; Niall Quinn
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 75 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0885-3185
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✦ Synopsis
Abstract
A progressive supranuclear palsy (PSP)‐like syndrome due to vascular or anoxic brain insult is rare. We describe a 65‐year‐old man with a progressive PSP‐like phenotype associated with hypoxic–ischemic bilateral striopallidal lesions, secondary to rupture of and subsequent surgery for a thoracic aortic aneurysm. After early extrapyramidal features, 10 months later he started to fall, and developed levator inhibition. A supranuclear gaze palsy for downgaze was documented 5.5 years after the insult. © 2005 Movement Disorder Society