𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Progressive reversion of clinical and molecular phenotype in a child with liver mitochondrial DNA depletion

✍ Scribed by Pierre-Henri Ducluzeau; Alain Lachaux; Raymonde Bouvier; Hervé Duborjal; Georges Stepien; Dominique Bozon; Bénédicte Mousson de Camaret


Book ID
118564602
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
203 KB
Volume
36
Category
Article
ISSN
0168-8278

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Depletion of mitochondrial DNA in liver
✍ Ulrich A. Walker; Jochen Bäuerle; Montse Laguno; Javier Murillas; Stefan Mauss; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB

The "D drug" HIV reverse-transcriptase inhibitors zalcitabine, didanosine, and stavudine are relatively strong inhibitors of polymerase-gamma compared with the "non-D drugs" zidovudine, lamivudine, and abacavir. D drugs deplete mitochondrial DNA (mtDNA) in cultured hepatocytes. This mtDNA depletion