## Abstract Progressive multifocal leukoencephalopathy (PML) is a severe neurological disorder due to JC virus (JCV) infection. Pre‐diagnostic biological markers and risk factors for PML are not well understood. We conducted a case–control study nested within the Multicenter AIDS Cohort Study to ex
✦ LIBER ✦
Progressive multifocal leukoencephalopathy in persons infected with human immunodeficiency virus, san francisco, 1981–1989
✍ Scribed by Dr. Sheila M. Gillespie; Dr. Yuan Chang; George Lemp; Ray Arthur; Susan Buchbinder; Dr. Anthony Steimle; James Baumgartner; Thomas Rando; Denesse Neal; Dr. George Rutherford; Lawrence Schonberger; Dr. Robert Janssen
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 726 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0364-5134
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Progressive multifocal leukoencephalopathy (PML) is a lytic infection of oligodendrocytes by the human papovavirus JC. Patients with defects in cell-mediated immunity are at risk for active disease: a usually lethal demyelination of the brain. PML develops in at least 4% of patients with the acquire