𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Progressive multifocal leucoencephalopathy with magnetic resonance imaging verification and therapeutic trials with interferon

✍ Scribed by K. Tashiro; S. Doi; F. Moriwaka; Y. Maruo; M. Nomura

Publisher
Springer
Year
1987
Tongue
English
Weight
881 KB
Volume
234
Category
Article
ISSN
0340-5354

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✦ Synopsis

Progressive multifocal leucoencephalopathy was diagnosed by magnetic resonance imaging (MRI) and brain biopsy in a 44-year-old woman, for whom therapeutic trials with various antiviral agents were made. Despite early diagnosis and treatment, her neurological deterioration and extension of MRI-detectable lesions were not halted for a period of about 8 months. After the introduction of intrathecal beta-interferon therapy, her neurological status and MRI findings became stable and showed minimal improvement. Early diagnosis of this fatal disorder is important and intrathecal interferon therapy should be considered.

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