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Progressive Dopaminergic Degeneration in the Chronic MPTPp Mouse Model of Parkinson’s Disease

✍ Scribed by Nicoletta Schintu; Lucia Frau; Marcello Ibba; Arianna Garau; Ezio Carboni; Anna R. Carta

Book ID
107678021
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
562 KB
Volume
16
Category
Article
ISSN
1029-8428

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## Abstract Atypical parkinsonian syndromes (APS) such as multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration are characterized by poor response to antiparkinsonian medication and rapid clinical deterioration. We used SPECT and [^123^I]β‐CIT as a label of dopamine