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Progressive cholinergic decline in Alzheimer's Disease: consideration for treatment with donepezil 23 mg in patients with moderate to severe symptomatology

✍ Scribed by Marwan Sabbagh; Jeffrey Cummings


Book ID
115009343
Publisher
BioMed Central
Year
2011
Tongue
English
Weight
147 KB
Volume
11
Category
Article
ISSN
1471-2377

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Tolerability of switching from donepezil
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This study investigates the tolerability, safety and efficacy of abrupt or stepwise switching from donepezil to memantine treatment in patients with moderate-to-severe Alzheimer's disease (AD). Outpatients (Table 1), !50 years, with dementia of the Alzheimer's type (DSM-IV-TR), MMSE 18 and receiving