Progressive central nervous system deterioration: A complication of advanced chronic lung disease of prematurity

Progressive oxidative damage in the cent

Progressive oxidative damage in the central nervous system of a murine model for juvenile Batten disease

✍ Jared W. Benedict; Crosby A. Sommers; David A. Pearce 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 531 KB

## Abstract Oxidative damage is a known contributor to the pathogenesis of neurodegenerative diseases. Juvenile Batten disease is a progressive neurodegenerative disorder of childhood that results from mutation in __Cln3__. We have performed an initial characterization of the oxidative burden throu