Cerebellar purkinje cell loss during lif
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Doulazmi, Mohamed; Fr�d�ric, Florence; Lemaigre-Dubreuil, Yolande; Hadj-Sahraoui
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Article
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1999
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John Wiley and Sons
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English
⚖ 264 KB
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The staggerer mutation causes dysgenesis of the cerebellar cortex in the homozygous mutant (Rora sg /Rora sg ). The mutation acts intrinsically within the Purkinje cells (PCs), leading to cytological abnormalities and a severe deficit in the number of these cells. In contrast, in the heterozygous st