Progression of monoaminergic dysfunction in Parkinson's disease: A longitudinal 18F-dopa PET study
β Scribed by Nicola Pavese; Maria Rivero-Bosch; Stephanie J. Lewis; Alan L. Whone; David J. Brooks
- Book ID
- 119331917
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 261 KB
- Volume
- 56
- Category
- Article
- ISSN
- 1053-8119
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## Abstract The aim of this study was to investigate the rate of progression in Parkinson's disease (PD) with 6β[^18^F]fluoroβLβdopa (FDOPA) positron emission tomography (PET). We investigated 21 patients with PD and eight healthy controls. Ten of the patients were de novo at the time of the first
## Abstract Little is known about the rate of progression of striatal dysfunction in subjects with __parkin__βlinked parkinsonism. Being a heterozygous __parkin__ gene carrier may confer susceptibility to Parkinson's disease (PD). In a previous ^18^Fβdopa PET study, we reported that 69% of carriers