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Progress toward the Cloning of CLN6, the Gene Underlying a Variant LINCL

✍ Scribed by K.J. Auger; A. Ajene; T. Lerner


Book ID
115639490
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
178 KB
Volume
66
Category
Article
ISSN
1096-7192

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The neuronal ceroid lipofuscinoses (NCLs) are a heterogeneous group of autosomal recessive neurodegenerative diseases comprising Batten and other related diseases plus numerous variants. They are characterized by progressive neuronal cell death. The CLN6 gene was recently identified, mutations in wh