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Progress in the unraveling of the endoplasmic reticulum stress/autophagy pathway and cancer: Implications for future therapeutic approaches

✍ Scribed by Stephen M. Schleicher; Luigi Moretti; Vinod Varki; Bo Lu

Book ID: 116413314
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 344 KB
Volume: 13
Category: Article
ISSN: 1368-7646
DOI: 10.1016/j.drup.2010.04.002

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## Abstract Prostate cancer cells are generally dependent on androgen stimulation mediated by the androgen receptor (AR) for growth and survival, and, therefore, hormonal manipulation, such as castration and/or the use of AR antagonists, results in a regression of the cancer. However, this treatmen