✦ LIBER ✦

Progress in the treatment of acute myeloid leukemia

✍ Scribed by Farhad Ravandi; Alan K. Burnett; Edward D. Agura; Hagop M. Kantarjian

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 131 KB
Volume: 110
Category: Article
ISSN: 0008-543X
DOI: 10.1002/cncr.23000

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Significant progress in understanding the mechanisms leading to the development of acute myeloid leukemia (AML) has led to the identification of numerous molecular abnormalities that may be responsible for leukemogenesis. Over the same period, large trials have established standard regimens combining cytotoxic agents for the treatment of patients with AML. Current research is attempting to better stratify patients by identifying risk factors responsible for resistance, and to discern ways for incorporating newer agents with specific and targeted activity into our standard regimens, Herein the recent developments in the diagnosis and treatment of AML are reviewed. Cancer 2007. © 2007 American Cancer Society.

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