Progress in Cell Cycle Research

✍ Scribed by Mark E. Ewen (auth.), Laurent Meijer, Armelle Jézéquel, Bernard Ducommun (eds.)

• Publisher: Springer US
• Year: 2000
• Tongue: English
• Leaves: 244
• Series: Progress in Cell Cycle Research
• Edition: 1
• Category: Library

✦ Synopsis

The "Progress in Cell Cycle Research" series is dedicated to serve as a collection of reviews on various aspects of the cell division cycle, with special emphasis on less studied aspects. We hope this series will continue to be helpful to students, graduates and researchers interested in the cell cycle area and related fields. We hope that reading of these chapters will constitute a "point of entry" into specific aspects of this vast and fast moving field of research. As PCCR4 is being printed several other books on the cell cycle have appeared (ref. 1-3) which should complement our series. This fourth volume of PCCR starts with a review on RAS pathways and how they impinge on the cell cycle (chapter 1). In chapter 2, an overview is presented on the links between cell anchorage -cytoskeleton and cell cycle progression. A model of the Gl control in mammalian cells is provided in chapter 3. The role of histone acetylation and cell cycle contriol is described in chapter 4. Then follow a few reviews dedicated to specific cell cycle regulators: the 14-3-3 protein (chapter 5), the cdc7/Dbf4 protein kinase (chapter 6), the two products of the pI6/CDKN2A locus and their link with Rb and p53 (chapter 7), the Ph085 cyclin-dependent kinases in yeast (chapter 9), the cdc25 phophatase (chapter 10), RCCI and ran (chapter 13). The intriguing phosphorylation­ dependent prolyl-isomerization process and its function in cell cycle regulation are reviewed in chapter 8.

✦ Table of Contents

Front Matter....Pages I-VIII
Relationship between Ras pathways and cell cycle control....Pages 1-17
Cell-anchorage, cell cytoskeleton, and Rho-GTPase family in regulation of cell cycle progression....Pages 19-25
The Continuum model and G1-control of the mammalian cell cycle....Pages 27-39
Histone acetylation and the control of the cell cycle....Pages 41-47
14-3-3 proteins and growth control....Pages 49-60
A Cdc7p-Dbf4p protein kinase activity is conserved from yeast to humans....Pages 61-69
Alternative product of the p16/CKDN2A locus connects the Rb and p53 tumor suppressors....Pages 71-81
Phosphorylation-dependent prolyl isomerization: a novel cell cycle regulatory mechanism....Pages 83-96
Functions of Pho85 cyclin-dependent kinases in budding yeast....Pages 97-106
Cell cycle regulation by the Cdc25 phosphatase family....Pages 107-114
Molecular mechanisms of the initiation of oocyte maturation: general and species-specific aspects....Pages 115-129
The activation of MAP kinase and p34cdc2/cyclin B during the meiotic maturation of Xenopus oocytes....Pages 131-143
Premature chromatin condensation caused by loss of RCC1....Pages 145-156
HTLV-I Tax and cell cycle progression....Pages 157-162
The cell cycle in protozoan parasites....Pages 163-183
Circadian control of cell division in unicellular organisms....Pages 185-192
Circadian variation of cell proliferation and cell cycle protein expression in man: Clinical implications....Pages 193-206
Molecular switches that govern the balance between proliferation and apoptosis....Pages 207-217
Molecular events that regulate cell proliferation: an approach for the development of new anticancer drugs....Pages 219-233
Abortive oncogeny and cell cycle-mediated events in Alzheimer disease....Pages 235-242
Back Matter....Pages 243-248

✦ Subjects

Animal Anatomy / Morphology / Histology; Human Genetics; Cancer Research; Biochemistry, general