[Progress in Brain Research] Down Syndro
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Fillat, Cristina
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Article
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2012
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Elsevier
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English
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Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of th