𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Progress in Brain Penetration Evaluation in Drug Discovery and Development

✍ Scribed by Liu, X.; Chen, C.; Smith, B. J.


Book ID
115477053
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2008
Tongue
English
Weight
347 KB
Volume
325
Category
Article
ISSN
0022-3565

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Adaptivity in drug discovery and develop
✍ Frank Bretz; Michael Branson; Carl-Fredrik Burman; Christy Chuang-Stein; Christo πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 219 KB πŸ‘ 1 views

## Abstract The development of novel drugs is becoming increasingly challenging, inefficient, and costly, as acknowledged by all major stakeholders of pharmaceutical products. Adaptive designs have attracted considerable attention in recent years, as they promise an increase in efficiency of the dr

Role of drug metabolism in drug discover
✍ Gondi N. Kumar; Sekhar Surapaneni πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 300 KB πŸ‘ 1 views

## Abstract Metabolism by the host organism is one of the most important determinants of the pharmacokinetic profile of a drug. High metabolic lability usually leads to poor bioavailability and high clearance. Formation of active or toxic metabolites will have an impact on the pharmacological and t